Particular birth faults will are present with ICSI-IVF, especially Beckwith-Wiedemann problem, Angelman disorder, hypospadias, and you may sex chromosome irregularities Routine IVF-ICSI (internet explorer, ICSI for all): Certain reproductive endocrinologists believe that most of the diligent need to have ICSI so you’re able to get rid of the chances of fertilization failure.